Ibuprofen – Widely Used Pain Reliever Disrupts Male Fertility


In 2017, a study concluded that fertility amongst Western men was on the decrease. Propelled by this, scientists are studying the reasons behind disruptions in male endocrinology. It has now been identified that ibuprofen affects male reproductive health. Ibuprofen, available as Advil and Motrin, is a widely used over-the-counter pain reliever.

The study, published in the journal of Proceedings of the National Academy of Sciences, found that ibuprofen alters the physiology of testicles, resulting in a condition known as ‘compensated hypogonadism’, common amongst elderly men. This condition is associated with reproductive and physical disorders. The data demonstrated that ibuprofen alters the endocrine system and induces compensated hypogonadism.

Read the study by accessing the Proceedings of the National Academy of Sciences of the United States of America (PNAS) page, via this link: